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Alprazolam, sold under the trade name Xanax, among others, is a short-acting benzodiazepine.[4] It is most commonly used in short term management of anxiety disorders, specifically panic disorder or generalized anxiety disorder (GAD).[5]Other uses include chemotherapy-induced nausea, together with other treatments.[3] GAD improvement occurs generally within a week.[6][7] Alprazolam is available by mouth.[3]

Common side effects include sleepiness, depression, headaches, feeling tired, dry mouth, and memory problems.[3] Some of the sedation and tiredness may improve within a few days.[8] Due to concerns about misuse, some do not recommend alprazolam as an initial treatment for panic disorder.[9] Withdrawal or rebound symptoms may occur if use is suddenly decreased.[3] Other rare risks include suicide, possibly due to loss of inhibition.[10] Gradually decreasing the dose over weeks or months may be required.[6] Alprazolam, like other benzodiazepines, acts through the GABAA receptor.[3]